Sanger and PacBio Launch Long-Read Effort to Decode Immune Gene Activity

A new collaboration between the Wellcome Sanger Institute and Pacific Biosciences (PacBio) will apply long-read, single-cell RNA sequencing to nearly 1,500 blood and gut samples in an effort to understand how gene activity shapes the human immune system. 

The initiative between Wellcome Sanger Institute and PacBio is among the first to apply this technology at scale and aims to identify RNA isoforms—alternate versions of gene transcripts—linked to conditions such as Inflammatory Bowel Disease (IBD) and individual treatment responses.

ARN isoforms are possible with Long read sequencing

Read More: https://www.sanger.ac.uk/news_item/new-collaboration-to-uncover-how-the-hidden-language-of-genes-shapes-our-immune-system/